Energy-precision trade-off in mitotic oscillators revealed by ATP modulation in artificial cells
Shiyuan Wang, Liam Yourston, Gembu Maryu, Yeonghoon Kim, Derek Walker, Usha Kadiyala, Qiong Yang
This study shows that mitotic oscillators trade energy for precision, with higher energy improving timing accuracy but reducing speed, and embryonic cell cycles balance speed and accuracy through metabolic compromise.
bioRxiv · Apr 9, 2026 · PreprintBiophysics