Qiong Yang

This study shows that mitotic oscillators trade energy for precision, with higher energy improving timing accuracy but reducing speed, and embryonic cell cycles balance speed and accuracy through metabolic compromise.

The paper examines temperature scaling in the early embryonic cell cycle across multiple species, finding similar activation energies and explaining deviations using computational models and experimental data.

The paper observes a transition from phase waves to trigger waves in Xenopus egg extracts and shows how these waves coordinate the cell cycle over long distances.

The paper investigates how substrate rigidity affects oscillatory behavior in zebrafish presomitic mesoderm cells, finding a switch-like transition at a critical rigidity threshold.

The paper investigates how nuclear compartmentalization affects mitotic timing by analyzing Cdk1 dynamics in synthetic cells with and without nuclei.

This study shows that cell cycle oscillations in Xenopus egg cytoplasm are robust to density changes but switch between oscillatory and stable states in a hysteresis loop.

The paper maps the cell cycle period landscape using synthetic cells and identifies polymorphic responses to PP2A inhibition.

This paper develops an artificial single-cell system to study mitotic oscillations, showing sustained oscillations over 30 cycles and highlighting energy supply's role in cell cycles.