Author

Lihui Gong

University of Saskatchewan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Alain Morejon Morales· 2 shared Anand KrishnaniD· 2 shared Andrew FreywaldiD· 2 shared Franco J. VizeacoumariD· 2 shared Frederick S. VizeacoumariD· 2 shared He DongiD· 2 shared Jared D. W. PriceiD· 2 shared Jeff Patrick Vizeacoumar· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alain Morejon Morales

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Organoid Pharmacotyping of Pancreatic Cancer Enables Functional Precision Oncology and Drug Repurposing

He Dong, Frederick S. Vizeacoumar, Yue Zhang, Nicholas Jette, Jared D. W. Price, Vincent Maranda, Lihui Gong, Tanya Freywald, Jeff Patrick Vizeacoumar, Mary Lazell-Wright, Saruul Uuganbayar, Jaylynn Quail, Alain Morejon Morales, Ayaan Rizvi, Rani Kanthan, , Franco J. Vizeacoumar

This paper uses patient-derived pancreatic cancer organoids to identify drug sensitivities linked to tumor differentiation and pathway mutations, revealing new therapeutic targets in chemoresistant tumors.

bioRxiv · Dec 3, 2025 · PreprintCancer Biology

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

Chelsea E. Cunningham, Frederick S. Vizeacoumar, Yue Zhang, Liliia Kyrylenko, Simon Both, Vincent Maranda, He Dong, Jared D. W. Price, Peng Gao, Konrad Wagner, Yingwen Wu, Mary Lazell-Wright, Ashtalakshmi Ganapathysamy, Rithik Hari, Kalpana Kalyanasundaram Bhanumathy, , Franco J. Vizeacoumar

The paper identifies synthetic dosage lethality targets for PLK1-overexpressing cancers using genome-wide screens and validates key hits to show their therapeutic potential.

Cell Genomics · May 9, 2025Peer-reviewedCancer Biology