Identification and characterization of ethR and ethA genes impacting the sensitivity of Mycobacterium abscessus to ethionamide
Xiaofan Zhang, Lijie Li, Ziwen Lu, Chaohui Duan, H. M. Adnan Hameed, Aweke Mulu Belachew, Cuiting Fang, Xirong Tian, Xinyue Wang, Hongyi Chen, Liqiang Feng, Matthew B. McNeil, Dongxin Liu, Shuai Wang, Tianyu Zhang
This study identifies EthR and EthA genes in Mycobacterium abscessus that mediate resistance to ethionamide, showing EthR is a more dominant resistance factor than NudC.
Microbiology Spectrum · Aug 28, 2026Peer-reviewedMicrobiology