Enalapril mitigates senescence and aging-related phenotypes by targeting antioxidative genes via phosphorylated Smad1/5/9
Wencong Lyu, Haochen Wang, Zhehao Du, Ran Wei, Jianuo He, Fanju Meng, Jinlong Bi, Lijun Zhang, Chao Zhang, Yiting Guan, Wei Tao
This study shows enalapril reduces cellular senescence and aging-related issues by enhancing antioxidative genes through phosphorylated Smad1/5/9, improving organ function and memory.
bioRxiv · Nov 27, 2024 · PreprintCell Biology