Epigenomic reprogramming of repetitive noncoding RNAs and IFN-stimulated genes by mutant KRAS
Roman E. Reggiardo, Sreelakshmi Velandi Maroli, Haley Halasz, Mehmet Ozgün Ozen, David Carrillo, Erin LaMontagne, Lila Whitehead, Eejung Kim, Shivani Malik, Jason D. Fernandes, Georgi K. Marinov, Eric Andrew Collisson, Utkan Demirci, Daniel H. Kim
This study identifies how mutant KRAS reprograms the noncoding transcriptome, upregulating repetitive noncoding RNAs and inducing IFN-stimulated genes through epigenetic and RNA-based mechanisms.
bioRxiv · Nov 4, 2020 · PreprintGenomics