Genome-wide epigenetic profiling of 5-hydroxymethylcytosine by long-read optical mapping
Tslil Gabrieli, Hila Sharim, Gil Nifker, Jonathan Jeffet, Tamar Shahal, Rani Arielly, Michal Levy‐Sakin, Lily Hoch, Nissim Arbib, Yael Michaeli, Yuval Ebenstein
This paper introduces a long-read optical mapping technology to profile 5-hydroxymethylcytosine (5-hmC) across the genome, revealing long-range epigenetic correlations and cell-to-cell variation.
bioRxiv · Feb 5, 2018 · PreprintGenomics