Author

Gil Nifker

Tel Aviv University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:DNA methylation· 3 Research Focus:variant calling· 3 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Yael Michaeli· 4 shared Yuval EbensteiniD· 4 shared Sapir Margalit· 3 shared Assaf Grunwald· 2 shared Benjamin DekeliD· 2 shared Dorit Omer· 2 shared Elmar G. WeinholdiD· 2 shared Jasline DeekiD· 2 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Yael Michaeli

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4 papers

Recent·Most cited

Optical Genome and Epigenome Mapping of Clear Cell Renal Cell Carcinoma

Sapir Margalit, Zuzana Tulpová, Yael Michaeli, Tahir Detinis Zur, Jasline Deek, Sivan Louzoun Zada, Gil Nifker, Assaf Grunwald, Yuval Scher, Leonie Schütz, Elmar G. Weinhold, Yehudit Gnatek, Dorit Omer, Benjamin Dekel, Eitan Friedman, Yuval Ebenstein

The paper uses optical genome and epigenome mapping to identify somatic alterations in early-stage clear cell renal cell carcinoma, revealing both known and novel genomic and epigenomic changes.

NAR Cancer · Jan 15, 2025Peer-reviewedGenomics

Long-Read Structural and Epigenetic Profiling of a Kidney Tumor-Matched Sample with Nanopore Sequencing and Optical Genome Mapping

Sapir Margalit, Zuzana Tulpová, Tahir Detinis Zur, Yael Michaeli, Jasline Deek, Gil Nifker, Rita Haldar, Yehudit Gnatek, Dorit Omer, Benjamin Dekel, Hagit Baris Feldman, Assaf Grunwald, Yuval Ebenstein

The paper compares optical genome mapping and nanopore sequencing for structural and epigenetic analysis of a kidney tumor, highlighting their strengths in variant detection and epigenetic profiling.

NAR Genomics and Bioinformatics · Jan 7, 2025Peer-reviewedGenomics

Simultaneous global labeling (SiGL) of 5-methylcytosine and 5-hydroxymethylcytosine by DNA alkylation with a synthetic cofactor and engineered methyltransferase

Sigal Avraham, Leonie Schütz, Larissa Käver, Andreas Dankers, Sapir Margalit, Yael Michaeli, Shahar Zirkin, Dmitry Torchinsky, Noa Gilat, Omer Bahr, Gil Nifker, Maya Koren‐Michowitz, Elmar G. Weinhold, Yuval Ebenstein

The paper introduces a method to simultaneously analyze 5-methylcytosine and 5-hydroxymethylcytosine in clinical samples, showing reduced 5-hydroxymethylcytosine in colorectal cancer and chronic lymphocytic leukaemia.

bioRxiv · Oct 31, 2022 · PreprintGenetics

Genome-wide epigenetic profiling of 5-hydroxymethylcytosine by long-read optical mapping

Tslil Gabrieli, Hila Sharim, Gil Nifker, Jonathan Jeffet, Tamar Shahal, Rani Arielly, Michal Levy‐Sakin, Lily Hoch, Nissim Arbib, Yael Michaeli, Yuval Ebenstein

This paper introduces a long-read optical mapping technology to profile 5-hydroxymethylcytosine (5-hmC) across the genome, revealing long-range epigenetic correlations and cell-to-cell variation.

bioRxiv · Feb 5, 2018 · PreprintGenomics