Author

Tamar Shahal

Tel Aviv UniversityORCID 0000-0002-3972-0844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:deconvolution· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Yuval EbensteiniD· 3 shared Elad SegeviD· 2 shared Gabi SheferiD· 2 shared Metsada Pasmanik‐ChoriD· 2 shared Naftali SterniD· 2 shared Thomas KonstantinovskyiD· 2 shared Yonit MarcusiD· 2 shared Assaf BuchiD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenomics

Yuval EbensteinORCID

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3 papers

Recent·Most cited

Epigenetic aging waves:Artificial intelligence detects clustering of switch points in DNA methylation rate in defined sex-dependent age periods

Elad Segev, Tamar Shahal, Thomas Konstantinovsky, Yonit Marcus, Gabi Shefer, Yuval Ebenstein, Metsada Pasmanik‐Chor, Naftali Stern

The paper uses machine learning to identify age-related switch points in DNA methylation trends, revealing three sex-dependent waves of epigenetic aging.

bioRxiv · Oct 2, 2022 · PreprintGenomics

Deconvolution of the epigenetic age discloses distinct inter-personal variability in epigenetic aging patterns

Tamar Shahal, Elad Segev, Thomas Konstantinovsky, Yonit Marcus, Gabi Shefer, Metsada Pasmanik‐Chor, Assaf Buch, Yuval Ebenstein, Paul Zimmet, Naftali Stern

The paper deconvolves epigenetic age to identify CpG sites responsible for accelerated and decelerated aging, revealing inter-personal variability in aging patterns.

Epigenetics & Chromatin · Mar 7, 2022Peer-reviewedDevelopmental Biology

Genome-wide epigenetic profiling of 5-hydroxymethylcytosine by long-read optical mapping

Tslil Gabrieli, Hila Sharim, Gil Nifker, Jonathan Jeffet, Tamar Shahal, Rani Arielly, Michal Levy‐Sakin, Lily Hoch, Nissim Arbib, Yael Michaeli, Yuval Ebenstein

This paper introduces a long-read optical mapping technology to profile 5-hydroxymethylcytosine (5-hmC) across the genome, revealing long-range epigenetic correlations and cell-to-cell variation.

bioRxiv · Feb 5, 2018 · PreprintGenomics