Lin-Chien Huang

BRCA1 and ELK-1 regulate Neural Progenitor Cell Fate in the Optic Tectum in response toVisual Experience in Xenopus laevis tadpoles

The paper identifies BRCA1 and ELK-1 as regulators of visual experience-dependent neural progenitor cell fate in Xenopus laevis optic tectum using transcriptomic and in vivo imaging analyses.

The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles

This study shows that elevated MMP-9 activity during early neurodevelopment causes neural circuit hyperconnectivity and behavioral deficits in Xenopus tadpoles, which can be reversed by blocking MMP-9.