Carlos D. Aizenman

Developmental Chlorpyrifos Exposure Disrupts Tectal Circuit Formation and Behavior in Xenopus laevis

This study shows that developmental chlorpyrifos exposure disrupts tectal circuit formation and leads to abnormal behavior in Xenopus laevis tadpoles.

Synapse specific alterations of autophagy are a hallmark of Danon disease

This study identifies synapse-specific autophagy alterations in Danon disease using a Xenopus tropicalis model, linking them to visual and cognitive impairments.

Regulation of Nav1.6-mediated sodium currents underlie the homeostatic control of neuronal intrinsic excitability in the optic tectum of the developing Xenopus laevis tadpole

The paper shows that Nav1.6 channels regulate intrinsic excitability in Xenopus tectal neurons in response to developmental and visual input changes, essential for normal circuit development.

The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles

This study shows that elevated MMP-9 activity during early neurodevelopment causes neural circuit hyperconnectivity and behavioral deficits in Xenopus tadpoles, which can be reversed by blocking MMP-9.

Behavioral assays to study neural development in Xenopus laevis tadpoles

The paper describes behavioral protocols to assess developmental abnormalities in Xenopus laevis tadpoles efficiently and effectively.

Early developmental exposure to Fluoxetine and Citalopram results in different neurodevelopmental outcomes

This study shows that early exposure to fluoxetine and citalopram in Xenopus tadpoles leads to distinct neurodevelopmental effects, including opposing behavioral and electrophysiological outcomes.