Author

Lina Zheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:scRNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Bo DingiD· 3 shared Wei Wang· 3 shared Adrian CamarenaiD· 1 shared Andre Wilberg· 1 shared Chris P. Walker· 1 shared David Medovoy· 1 shared Hannah R. DueckiD· 1 shared Jae Mun (Hugo) Kim· 1 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioinformatics

Bo DingORCID

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Author profile →

3 papers

Recent·Most cited

Assessment of single cell RNA-seq normalization methods

Bo Ding, Lina Zheng, Wei Wang

This study evaluates seven single cell RNA-seq normalization methods using diluted RNA data, finding that methods incorporating spike-in ERCC RNA outperform those without.

bioRxiv · Jul 17, 2016Bioinformatics

Assessing the measurement transfer function of single-cell RNA sequencing

Hannah R. Dueck, Rizi Ai, Adrian Camarena, Bo Ding, Reymundo Dominguez, Oleg V. Evgrafov, Jian-Bing Fan, Stephen A. Fisher, Jennifer S. Hernstein, Tae Kyung Kim, Jae Mun (Hugo) Kim, Ming-Yi Lin, Rui Liu, William J. Mack, Sean McGroty, , Junhyoung Kim

This study evaluates the performance of three scRNA-seq methods through controlled experiments, finding they reliably detect genes above 5-10 molecules with linear measurement transfer functions.

bioRxiv · Mar 24, 2016 · PreprintGenomics

Targeted mutations on 3D hub loci alter spatial interaction environment

Bo Ding, Lina Zheng, David Medovoy, Wei Wang

The paper identifies cancer-specific genotype variations that target 3D chromosomal hubs, altering local interactions and revealing principles of genome organization.

bioRxiv · Nov 9, 2015 · PreprintBiophysics