Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
Jie Zheng, Valeriia Haberland, Denis A. Baird, Venexia M. Walker, Philip Haycock, Mark R. Hurle, Alex Gutteridge, Pau Erola, Yi Liu, Shan Luo, Jamie W. Robinson, Tom G. Richardson, James R Staley, Benjamin Elsworth, Stephen Burgess, , Tom R. Gaunt
This paper uses Mendelian randomization and colocalization to identify causal relationships between plasma proteins and disease phenotypes, finding 111 putatively causal effects.
Nature Genetics · Sep 7, 2020Peer-reviewedGenetics