CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single stranded DNA gaps
Lindsey M Pale, Jude B. Khatib, Alexandra Nusawardhana, Joshua Straka, Claudia M. Nicolae, George‐Lucian Moldovan
The paper identifies the HELQ-RAD52 axis as a regulator of cisplatin-induced ssDNA gap processing through CRISPR screens in human cells.
Nucleic Acids Research · Oct 16, 2024Peer-reviewedCancer Biology