Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease
Hyun‐Sik Yang, Ling Teng, Daniel Kang, Vilas Menon, Tian Ge, Hilary K. Finucane, Aaron P. Schultz, Michael J Properzi, Hans‐Ulrich Klein, Lori Beth Chibnik, Julie A. Schneider, David Alan Bennett, Timothy J. Hohman, Richard P Mayeux, Keith A. Johnson, , Reisa Anne Sperling
The paper derives cell-type-specific Alzheimer's disease polygenic risk scores and shows their associations with distinct pathological features in AD.
Nature Communications · Nov 30, 2023Peer-reviewedGenetic & Genomic Medicine