Author
Zhejiang University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Lingdong Shen, Linlin Chao, Tang Liu, Qi Liu, Guowei Zhou, Hao Wang, Xinyue Dong, Tianhong Li, Xiaoming Zhang, jinren Ni
ProteinSage uses structural constraints during pretraining to improve protein language modeling with less data, achieving competitive performance on structure-aware tasks.
bioRxiv · Sep 9, 2026 · PreprintBioinformatics
Ruofan Jin, Yucheng Guo, Yuanhao Qu, Ming Yang, Chun Shang, Qirong Yang, Linlin Chao, Yi Zhou, Rui Min Xu, Ziyao Xu, Ruhong Zhou, Zaixi Zhang, Mengdi Wang, Xiaoming Zhang, Le Cong
BioLab uses a multi-agent system with foundation models to autonomously design and validate antibodies, achieving superior performance compared to existing methods.
bioRxiv · Sep 3, 2025 · PreprintBioinformatics
Chaozhong Liu, Linlin Chao, Shaomin Ji, Hao Wang, Guowei Zhou, J. X. Zheng, Dubeiqi Hong, Yucheng Guo, Taorui Jiang, Zhangyang Gao, Ming Yang, Jianfeng Pan, Stan Ziqing Li, Xiaomin Zhang
This paper introduces modality-chain reasoning for multimodal protein modeling and design, showing improved performance in structure prediction, inverse folding, and fitness prediction compared to existing models.
bioRxiv · Jul 21, 2025 · PreprintBioinformatics
Zaixi Zhang, Ruofan Jin, Linlin Chao, Guangxue Xu, Yikun Zhang, Guowei Zhou, Di Yin, Yingqing Guo, Yaqi Fu, Yukang Yang, Kaixuan Huang, Xiaotong Wang, Junze Zhang, Yujie Yang, Qirong Yang, , Le Cong
RNAGenesis is a foundation model for RNA therapeutics that integrates sequence, structure, and function prediction, achieving state-of-the-art performance on multiple tasks and enabling functional RNA design.
bioRxiv · Dec 30, 2024 · PreprintBioinformatics