Linnea M. Kriese

Polysialic acid is a versatile marker for retinal Müller glia in common vertebrate model organisms and systems

This paper identifies polysialic acid (polySia) as a conserved marker for Muller glia across vertebrates and introduces tools to detect it in various species and models.

Prominin-1 null Xenopus laevis develop subretinal drusenoid-like deposits, cone-rod dystrophy, and dysmorphic retinal pigment epithelium.

This study shows that prom1-null Xenopus laevis develop subretinal drusenoid-like deposits and retinal degeneration, indicating RPE dysfunction precedes photoreceptor loss.