Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
Evelien M. Bunnik, Kate B. Cook, Nelle Varoquaux, Gayani Batugedara, Jacques G. Prudhomme, Anthony Cort, Lirong Shi, Chiara Andolina, Leila Saxby Ross, Declan Brady, David A. Fidock, François Henry Nosten, Rita Tewari, Photini Sinnis, Ferhat Ay, , Karine G. Le Roch
This study examines changes in genome organization during the transmission stages of Plasmodium parasites and finds that three-dimensional genome structure is linked to transcriptional activity of gene families involved in pathogenesis and immune evasion.
Nature Communications · May 9, 2018Peer-reviewedSystems Biology