Author

Leila Saxby Ross

Columbia University Irving Medical CenterORCID 0000-0003-4360-5213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:plant (other)· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

David A. FidockiD· 3 shared Photini SinnisiD· 3 shared Abhai K. TripathiiD· 2 shared Anne‐Catrin UhlemanniD· 2 shared Eva Gil‐IturbeiD· 2 shared Felix D. RozenbergiD· 2 shared Filippo ManciaiD· 2 shared Godfree MlamboiD· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

David A. FidockORCID

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4 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 27, 2024

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

Mariko Kanai, Sachel Mok, Tomas Yeo…·David A. Fidock

This study identifies DMT1 and a chromosome 12 locus, including FtsH1, as novel contributors to Plasmodium falciparum resistance to quinine, alongside the known pfcrt gene.

1 citation

plant (other)statistical model

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GenomicsbioRxivPreprintFeb 18, 2024

Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks

Alexander C. Bashore, Chenyi Xue, Eunyoung Kim…·Muredach P. Reilly

The paper uses multimodal single-cell profiling to identify diverse monocyte subtypes and links them to cardiovascular disease risk factors.

DOI 10.1101/2024.02.18.580913

humanmouse

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GenomicsScience AdvancesPeer-reviewedNov 8, 2023

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Sachel Mok, Tomas Yeo, Davin Hong…·David A. Fidock

The paper identifies genetic determinants of multidrug resistance in Plasmodium falciparum and their impact on parasite fitness and drug susceptibility.

35 citationstop 1%

plant (other)experimental assay

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Systems BiologyNature CommunicationsPeer-reviewedMay 9, 2018

Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

Evelien M. Bunnik, Kate B. Cook, Nelle Varoquaux…·Karine G. Le Roch

This study examines changes in genome organization during the transmission stages of Plasmodium parasites and finds that three-dimensional genome structure is linked to transcriptional activity of gene families involved in pathogenesis and immune evasion.

130 citationstop 1%

humanChIP-seq

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