Author

Lisa Dwane

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexandra BeckiD· 1 shared Andrew Roger BassettiD· 1 shared Ching Chiek KohiD· 1 shared Emanuel GonçalvesiD· 1 shared Emily Souster· 1 shared Emre KarakoçiD· 1 shared Inigo Barrio‐HernandeziD· 1 shared Lykourgos‐Panagiotis ZalmasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexandra BeckORCID

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1 paper

Recent·Most cited

Genetic interaction library screening with a next-generation dual guide CRISPR system

Thomas Burgold, Emre Karakoç, Emanuel Gonçalves, Inigo Barrio‐Hernandez, Lisa Dwane, Romina Silva, Emily Souster, Mamta Sharma, Alexandra Beck, Ching Chiek Koh, Lykourgos‐Panagiotis Zalmas, Mathew J. Garnett, Andrew Roger Bassett

The paper introduces a next-generation dual guide CRISPR system for efficient genetic interaction screening, achieving low undesired guide pairs and balanced expression, and demonstrates its application in colorectal cancer cells.

Nature Communications · Dec 6, 2025Peer-reviewedMolecular Biology