Author

Romina Silva

Wellcome Sanger InstituteORCID 0000-0001-5429-0152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexandra BeckiD· 1 shared Andrew Roger BassettiD· 1 shared Ching Chiek KohiD· 1 shared Emanuel GonçalvesiD· 1 shared Emily Souster· 1 shared Emre KarakoçiD· 1 shared Inigo Barrio‐HernandeziD· 1 shared Lisa Dwane· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexandra BeckORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedDec 6, 2025

Genetic interaction library screening with a next-generation dual guide CRISPR system

Thomas Burgold, Emre Karakoç, Emanuel Gonçalves…·Andrew Roger Bassett

The paper introduces a next-generation dual guide CRISPR system for efficient genetic interaction screening, achieving low undesired guide pairs and balanced expression, and demonstrates its application in colorectal cancer cells.

14 citationstop 5%

humanCRISPR screen

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