Author

Longfei Hu

Singleron Biotechnologies (china)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jue FaniD· 3 shared Yan ZhangiD· 2 shared Ai‐Wu KeiD· 1 shared Fei LaniD· 1 shared Guo‐Ming ShiiD· 1 shared Jia FaniD· 1 shared Jiabin CaiiD· 1 shared Jian ZhouiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Jue FanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CellClear: Enhancing Single-cell RNA Data Quality via Biologically-Informed Ambient RNA Correction

Wanxiang Huang, Longfei Hu, Zhengzong Qian, Jue Fan

CellClear improves single-cell RNA data quality by correcting ambient RNA, enhancing cell type classification accuracy without altering native cell information.

bioRxiv · Aug 5, 2024 · PreprintBioinformatics

Single-cell Analysis of ACE2 Expression in Human Kidneys and Bladders Reveals a Potential Route of 2019-nCoV Infection

Wei Lin, Jue Fan, Longfei Hu, Yan Zhang, Joshua Daniel Ooi, Ting Meng, Peng Jin, Xiang Ding, Longkai Peng, Lei Song, Rong Tang, Zhou Sheng Xiao, Xiang Ao, Xiangcheng Xiao, Qiaoling Zhou, , Yong Zhong

The paper analyzes ACE2 expression in human kidney and bladder cells to assess the potential for 2019-nCoV infection through the urinary system.

Chinese Medical Journal · Apr 20, 2021Peer-reviewedGenomics

Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection

Xiaoqiang Chai, Longfei Hu, Yan Zhang, Weiyu Han, Lu Zhou, Ai‐Wu Ke, Jian Zhou, Guo‐Ming Shi, Nan Fang, Jia Fan, Jiabin Cai, Jue Fan, Fei Lan

In healthy human liver scRNA-seq, ACE2 is detected in 59.7% of cholangiocytes but 2.6% of hepatocytes, so 2019-nCoV may target bile duct cells rather than hepatocytes.

bioRxiv · Feb 3, 2020 · PreprintGenomics✦ In-depth digest