Reconstructing tumor evolution without chromosomal instability reveals in vivo determinants of therapeutic response
Ruhollah Moussavi-Baygi, Matthew J. Ryan, Woogwang Sim, Samuel B Hoelscher, Valbona Luga, Arun A. Chandrakumar, Lore Hoes, Junghwa Cha, Young Sun Lee, Katelyn Herm, Ben Doron, Danika Bakke, Sharon Wu, C.K. Cornelia Ding, Bradley A. Stohr, , Rohit Bose
This study develops an in vivo platform called SETs to reconstruct tumor evolution without chromosomal instability, identifying therapeutic response determinants in prostate cancer.
bioRxiv · Mar 17, 2025 · PreprintCancer Biology