Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma
Mallikarjun Bidarimath, Coulter Q. Ralston, Nandini Bidarimath, Ian M. Rose, Darianna Colina, Elisa Schmoeckel, Andrew K. Godwin, Doris Mayr, Lora Hedrick Ellenson, Andrea Flesken‐Nikitin, Alexander Yu. Nikitin
This study identifies KRT5-expressing cells as cancer-propagating cells in HGSC that depend on an OPN-producing niche for survival and chemoresistance.
Cancer Heterogeneity and Plasticity · Apr 25, 2026Peer-reviewedCancer Biology