Author

Darianna Colina

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Yu. NikitiniD· 1 shared Andrea Flesken‐NikitiniD· 1 shared Andrew K. GodwiniD· 1 shared Azmain AlamgiriD· 1 shared Cara M. RobertusiD· 1 shared Christopher A. AlabiiD· 1 shared Connor MonticelloiD· 1 shared Coulter Q. RalstoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Alexander Yu. NikitinORCID

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2 papers

Recent·Most cited

Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo

Tianzheng Ye, Azmain Alamgir, Cara M. Robertus, Darianna Colina, Connor Monticello, Thomas Connor Donahue, Lauren Hong, Sophia Vincoff, Shrey Goel, Peter Fekkes, Luis Miguel Camargo, Kieu Lam, James Heyes, David A. Putnam, Christopher A. Alabi, , Matthew P. DeLisa

This paper develops programmable protein degraders (uAbs) that selectively knock down pathogenic β-catenin in vitro and in vivo, reducing tumor cell survival and proliferation.

Science Advances · Aug 28, 2026Peer-reviewedBioengineering

Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma

Mallikarjun Bidarimath, Coulter Q. Ralston, Nandini Bidarimath, Ian M. Rose, Darianna Colina, Elisa Schmoeckel, Andrew K. Godwin, Doris Mayr, Lora Hedrick Ellenson, Andrea Flesken‐Nikitin, Alexander Yu. Nikitin

This study identifies KRT5-expressing cells as cancer-propagating cells in HGSC that depend on an OPN-producing niche for survival and chemoresistance.

Cancer Heterogeneity and Plasticity · Apr 25, 2026Peer-reviewedCancer Biology