Neuropilin-1 expression by solid tumors impairs CAR T cell function
Louise Condon, Marie Bouillié, Jaime R. Fuentealba, Michael Saitakis, Olivier Hermine
This study investigates how Neuropilin-1 (NRP-1) on solid tumors affects CAR T cell function, finding that NRP-1 transfer via trogocytosis may impair CAR T cell activity.
bioRxiv · Sep 16, 2025 · PreprintImmunology