Author

Lucas Dyer

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

David PincusiD· 3 shared Asif AliiD· 2 shared Surabhi ChowdharyiD· 2 shared Annisa DeaiD· 1 shared Arjun S. RamaniD· 1 shared Benjamin A. DoraniD· 1 shared Cameron Williams· 1 shared Jennifer T KrystosekiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

David PincusORCID

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Author profile →

3 papers

Recent·Most cited

Chaperone condensates buffer the heat shock response against pleiotropic inputs

Lucas Dyer, Jennifer T Krystosek, Sean A. Martin, Cameron Williams, Leah Chaney Winner, Asif Ali, Surabhi Chowdhary, David Pincus

The paper shows that chaperone condensates specifically buffer the heat shock response, setting activation thresholds and ensuring specificity to heat shock in budding yeast.

bioRxiv · Jul 30, 2026 · PreprintCell Biology

Physiological architecture and evolutionary origins of cellular adaptability

Annisa Dea, Yongqing Lan, Benjamin A. Doran, Asif Ali, Maya G. Igarashi, Lucas Dyer, Valeryia Aksianiuk, David Pincus, Arjun S. Raman

The paper shows that cellular adaptability is shaped by evolutionary history through a prioritization hierarchy of transcriptional responses to environmental cues.

bioRxiv · Apr 11, 2026 · PreprintCell Biology

Emergent 3D genome reorganization from the stepwise assembly of transcriptional condensates

Surabhi Chowdhary, Sarah Paracha, Lucas Dyer, David Pincus

The paper shows transcriptional condensates form stepwise in yeast to enable graded and 3D gene control during heat shock response.

bioRxiv · Feb 23, 2025 · PreprintMolecular Biology