Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction
Naoko Hara, Dorota S. Raclawska, Leslie E. Morgan, James C. Needell, Lucie Dao, Ayako Kato, Ana Maria Jaramillo, Patrick S. Hume, Fernando Holguín, William J. Janssen, Eszter K. Vladar, Christopher M. Evans
This study identifies fucosyltransferase 2 (Fut2) as essential for mucin fucosylation, which contributes to allergic airway hyperreactivity and mucus obstruction in mice.
American Journal of Respiratory Cell and Molecular Biology · Oct 24, 2024Peer-reviewedPhysiology