Author

Lucy A. Stebbings

Wellcome Sanger Institute

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

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Alba Dalmases· 1 shared Beatríz BellosilloiD· 1 shared Carla Daniela Robles‐EspinozaiD· 1 shared Clara O. MontagutiD· 1 shared Constantine AlifrangisiD· 1 shared Francesco IorioiD· 1 shared Graham R. Bignell· 1 shared Iñigo MartincorenaiD· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperGenetics

Alba Dalmases

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1 paper

Recent·Most cited

GeneticsGenome ResearchPeer-reviewedApr 1, 2017

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Jonathan S. Brammeld, Mia Petljak, Iñigo Martincorena…·Ultan McDermott

This paper describes a method to identify drug resistance mutations in cancer using genome-wide chemical mutagenesis and next-generation sequencing, enabling the discovery of both known and novel resistance mechanisms.

23 citations

humanwhole-genome sequencing

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