Human Lung Alveolar Model with an Autologous Innate and Adaptive Immune Compartment
Linda Steinacher, Bruno Gjeta, Marisa Pimentel Mendes, Floriana Cremasco, Irineja Cubela, Marina Bellavista, Laura Gaspa-Toneu, Luisa Lauer, Qianhui Yu, Ryo Okuda, Barzin Y. Nabet, Velimir Gayevskiy, Michel Siegel, Axel Ducret, Evodie Lassalle, , Lauriane Cabon
This paper develops human lung alveolar immuno-organoids with autologous immune cells to model immune-epithelial interactions and study inflammation-related pulmonary side effects.
bioRxiv · Feb 27, 2025 · PreprintCell Biology