Author

Christelle Zundel

F. Hoffmann-La Roche AG

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Nadine Stokar‐RegenscheitiD· 3 shared Alex OdermattiD· 2 shared Chiara Zanini· 2 shared Claire Simonneau· 2 shared Luisa Bell· 2 shared Roberto VillaseñoriD· 2 shared A. Rizkallah· 1 shared Adrian B. RothiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Nadine Stokar‐RegenscheitORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells

Luisa Bell, Shane Clerkin, Filiz Sila Rizalar, A. Rizkallah, Nadine Stokar‐Regenscheit, Xandor M. Spijkers, Nienke R. Wevers, Claire Simonneau, Angélique Augustin, Barbara Höllbacher, Lia D’Abate, Joanna Ficek, Kim Schneider, Désirée von Tell, Thomas L. Maurissen, , Roberto Villaseñor

The paper investigates how ApoE4 affects intracellular trafficking and iron homeostasis in human brain endothelial cells derived from iPSCs, showing altered endosomal organization and iron levels.

Stem Cell Reports · Aug 21, 2025Peer-reviewedCell Biology

Human Lung Alveolar Model with an Autologous Innate and Adaptive Immune Compartment

Linda Steinacher, Bruno Gjeta, Marisa Pimentel Mendes, Floriana Cremasco, Irineja Cubela, Marina Bellavista, Laura Gaspa-Toneu, Luisa Lauer, Qianhui Yu, Ryo Okuda, Barzin Y. Nabet, Velimir Gayevskiy, Michel Siegel, Axel Ducret, Evodie Lassalle, , Lauriane Cabon

This paper develops human lung alveolar immuno-organoids with autologous immune cells to model immune-epithelial interactions and study inflammation-related pulmonary side effects.

bioRxiv · Feb 27, 2025 · PreprintCell Biology

Advanced Tissue Technologies of Blood-Brain Barrier Organoids as High Throughput Toxicity Readouts in Drug Development

Luisa Bell, Claire Simonneau, Chiara Zanini, Elena Kassianidou, Christelle Zundel, Rachel Neff, Bernd Steinhuber, Marco Tecilla, Alex Odermatt, Roberto Villaseñor, Nadine Stokar‐Regenscheit

Paraffin histology, multiplex immunofluorescence and MALDI imaging work on blood-brain barrier organoids; an AI apoptosis detector on hematoxylin-eosin slides (F1 0.817 vs pathologists) tracked staurosporine dose responses.

Heliyon · Dec 2, 2024Peer-reviewedPathology✦ In-depth digest