mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice
Luke K. Burke, Tamana Darwish, Althea R Cavanaugh, Sam Virtue, Emma Roth, Joanna Morro, Shun-Mei Liu, Jing Xia, Jeffrey W. Dalley, Keith Burling, Streamson C. Chua, Toni Vidal-Puig, Gary J. Schwartz, Clémence Blouet
This study shows mTORC1 in AGRP neurons integrates food-related cues to control iBAT thermogenesis in mice, linking energy availability to adaptive energy expenditure.
eLife · May 22, 2017Peer-reviewedNeuroscience