Author

Lydia M. Parkinson

Wellcome/MRC Cambridge Stem Cell Institute

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Developmental Biology· 1

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Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

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Anna PhilpottiD· 1 shared Lewis ChaytoriD· 1 shared William F. BeckmaniD· 1 shared

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2025-2025 · peak 1/yr

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Anna PhilpottORCID

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1 paper

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Developmental BiologyDevelopmentPeer-reviewedJun 2, 2025

Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific

William F. Beckman, Lydia M. Parkinson, Lewis Chaytor, Anna Philpott

The paper shows ASCL1 controls distinct transcriptional programs in different cell cycle stages by binding chromatin at promoters and enhancers, with G1 arrest required for neuronal differentiation.

4 citations

humanChIP-seq

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