Author

Lewis Chaytor

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0009-0000-4231-0726Unclaimed ORCID profile · follow to get notified of new preprints

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Developmental Biology· 1

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Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

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Anna PhilpottiD· 1 shared Lydia M. Parkinson· 1 shared William F. BeckmaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperDevelopmental Biology

Anna PhilpottORCID

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1 paper

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedJun 2, 2025

Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific

William F. Beckman, Lydia M. Parkinson, Lewis Chaytor, Anna Philpott

The paper shows ASCL1 controls distinct transcriptional programs in different cell cycle stages by binding chromatin at promoters and enhancers, with G1 arrest required for neuronal differentiation.

4 citations

humanChIP-seq

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