Author

M. A. Friedman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. G. Buettmann· 2 shared G. A. Hoppock· 2 shared H. J. Donahue· 2 shared A. M. White· 1 shared C. Buchholz· 1 shared C. E. Berndsen· 1 shared D. H. Kohn· 1 shared G. M. Goldscheitter· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

E. G. Buettmann

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genetic Diversity Modulates The Physical And Transcriptomic Response Of Skeletal Muscle To Simulated Microgravity

Y. Zeineddine, M. A. Friedman, E. G. Buettmann, L. B. Abraham, G. A. Hoppock, H. J. Donahue

This study shows that genetic diversity affects skeletal muscle response to simulated microgravity, with some strains experiencing more muscle loss than others.

bioRxiv · Jun 27, 2023 · PreprintBioengineering

Connexin 43 and Cell Culture Substrate Differentially Regulate OCY454 Osteocytic Differentiation and Signaling to Primary Bone Cells

G. A. Hoppock, E. G. Buettmann, J. A. Denisco, G. M. Goldscheitter, S. N. Condyles, O. J. Juhl, M. A. Friedman, Y. Zhang, H. J. Donahue

This study compares 3D and 2D culture of Cx43-deficient OCY454 osteocytes, finding that 3D cultures enhance differentiation and bone remodeling factor secretion, while Cx43 deficiency increases signaling to promote osteoblast and osteoclast formation.

bioRxiv · Jun 23, 2023Cancer Biology

Structural and functional analysis of the human Cone-rod homeobox transcription factor

P.-M. Clanor, C. Buchholz, J. E. Hayes, M. A. Friedman, A. M. White, R. A. Enke, C. E. Berndsen

This study presents the first structural analysis of the human CRX homeodomain using bioinformatics and SAXS, revealing its monomeric structure and DNA-binding capability.

bioRxiv · Jan 9, 2022Biochemistry

Calcium- and Phosphorus-Supplemented Diet Increases Bone Volume After Four Weeks of High-Speed Treadmill Exercise in Adult Mice

M. A. Friedman, D. H. Kohn

This study shows that combining high-speed treadmill exercise with a calcium- and phosphorus-supplemented diet increases cortical and trabecular bone mass in adult mice compared to exercise alone or a standard diet.

bioRxiv · Oct 13, 2020 · PreprintPhysiology