M. A. Hanson

Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in Drosophila

The paper investigates how bacteria in the environment influence the evolution of antimicrobial peptides in Drosophila.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

This study investigates the role of antimicrobial peptides (AMPs) in aging in Drosophila, finding that they do not directly affect lifespan but prevent dysbiosis, which improves lifespan.

Drosophila immunity: The Drosocin gene encodes two host defence peptides with pathogen-specific roles

This study identifies two host defence peptides encoded by the Drosocin locus in Drosophila, each with specific roles against different pathogens, and shows how a polymorphism affects susceptibility.

Cecropins contribute to Drosophila host defense against fungal and Gram-negative bacterial infection

This study shows Cecropins in Drosophila are important for defense against Gram-negative bacteria and fungi, using genetic deletion and mutant analysis.

Drosophila antimicrobial peptides and lysozymes regulate gut microbiota composition and abundance

This study shows that antimicrobial peptides and lysozymes in Drosophila regulate gut microbiota composition and abundance, with their effects exacerbated during aging.

Repeated truncation of a modular antimicrobial peptide gene for neural context

The paper shows that Baramicin gene paralogs in Drosophila result from duplication and truncation, producing non-immune products with neural functions.

The Drosophila Baramicin polypeptide gene protects against fungal infection

This study identifies a novel Drosophila antifungal peptide gene, Baramicin A, showing its role in antifungal resistance and immune response.

Genetic description of Manania handi and Manania gwilliami

The paper confirms the genetic identity of Manania handi samples and provides additional sequence data for M. handi and H. sanjuanensis to aid in future staurozoan identification.

Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

This study uses CRISPR to knockout Drosophila AMPs and shows they act synergistically or additively against Gram-negative bacteria and fungi, with specific AMPs targeting specific pathogens.

More than black and white: complex relationships involving serine proteases regulate the Toll pathway and the melanization response in Drosophila

This study identifies two distinct serine protease pathways regulating melanization and Toll signaling in Drosophila, revealing previously hidden roles of Hayan and Sp7.