The antimicrobial peptide Defensin cooperates with Tumour Necrosis Factor to drive tumour cell death in Drosophila
J.-P. Parvy, Y. Yu, A. Dostalova, S. Kondo, A. Kurjan, P. Bulet, B. Lemaitre, M. Vidal, J. Cordero
This study shows Defensin, an antimicrobial peptide, works with Tumour Necrosis Factor to kill tumour cells in Drosophila, demonstrating an in vivo anti-cancer role for an endogenous AMP.
bioRxiv · Jan 19, 2019Cancer Biology