Author

M. A. Koch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:development & morphogenesis· 3 Organism:plant (other)· 3 Assay:whole-genome sequencing· 3 Organism:Arabidopsis· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2

Frequent Co-Authors

L. Yant· 4 shared C. Moore· 2 shared E. M. Wolf· 2 shared F. Kolar· 2 shared J. Koch· 2 shared L. Cowan· 2 shared M. A. Lysak· 2 shared M. Zhou· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersEvolutionary Biology

L. Yant

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Impact of whole-genome duplications on structural variant evolution in the plant genus Cochlearia

T. Hamala, C. Moore, L. Cowan, M. Carlile, D. Gopaulchan, M. K. Brandrud, S. Birkeland, M. Loose, F. Kolar, M. A. Koch, L. Yant

This study examines how whole-genome duplications in Cochlearia plants increase structural variant diversity and its impact on adaptation to environmental changes.

bioRxiv · Sep 29, 2023Evolutionary Biology

Kinetochore and ionomic adaptation to whole genome duplication

S. M. Bray, T. Hamala, M. Zhou, S. Busoms, S. Fischer, S. D. Desjardins, T. Mandakova, C. Moore, T. C. Mathers, L. Cowan, P. Monnahan, J. Koch, E. M. Wolf, M. A. Lysak, F. Kolar, , L. Yant

This study identifies genetic adaptations to whole genome duplication in Cochlearia species, highlighting kinetochore and ion transport gene changes across multiple WGD events.

bioRxiv · Sep 27, 2023 · PreprintEvolutionary Biology

Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-specific inflammation

V. P. O'Brien, Y. Kang, M. K. Shenoy, G. Finak, W. C. Young, J. Dubrulle, L. Koch, A. E. R. Martinez, J. A. Snow, J. Williams, E. Donato, S. K. Batra, C. C. Yeung, S. Bullman, M. A. Koch, , N. R. Salama

The paper identifies a Muc4-expressing metaplastic gastric cell type in mice driven by H. pylori inflammation and shows its association with proliferation in human gastric cancer.

bioRxiv · Dec 20, 2022 · PreprintMicrobiology

Global Phylogeny of the Brassicaceae Provides Important Insights into Gene Discordance

K. P. Hendriks, C. Kiefer, I. A. Al-Shehbaz, C. D. Bailey, A. A. C. Hooft van Huysduynen, L. Nikolov, L. Nauheimer, A. R. Zuntini, D. A. German, A. Franzke, M. A. Koch, M. A. Lysak, O. Toro-Nunez, B. Ozudogru, V. R. Invernon, , Fore

This paper presents a comprehensive Brassicaceae phylogeny, identifies cytonuclear discordance due to hybridization, and proposes new tribes, providing a tool for biodiversity and plant biology studies.

bioRxiv · Sep 1, 2022Evolutionary Biology

Evolutionary footprints of a cold relic in a rapidly warming world

E. Wolf, E. Gaquerel, M. Scharmann, L. Yant, M. A. Koch

This paper studies the evolutionary history of the genus Cochlearia, revealing its adaptation to cold environments through polyploid evolution and metabolomics insights.

bioRxiv · Jul 11, 2021Evolutionary Biology

Convergence and novelty in adaptation to whole genome duplication in three independent polyploids

S. M. Bray, E. M. Wolf, M. Zhou, S. Busoms, M. Bohutinska, P. Paajanen, P. Monnahan, J. Koch, S. Fischer, M. A. Koch, L. Yant

The paper investigates adaptation to whole genome duplication in three polyploid species, finding flexible gene recruitment and varying convergence in adaptive processes.

bioRxiv · Mar 31, 2020 · PreprintEvolutionary Biology