Author

M. A. Kostiainen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

V. Linko· 3 shared E. Anaya-Plaza· 2 shared A. Heuer-Jungemann· 1 shared A. Keller· 1 shared A. Shaukat· 1 shared B. Shen· 1 shared C. Jonkergouw· 1 shared D. Fedorov· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBioengineering

V. Linko

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Supercharged Fluorescent Protein-Apoferritin Cocrystals for Lighting Applications

M. Patrian, A. Shaukat, M. Nieddu, J. A. Banda-Vazquez, J. V. I. Timonen, J. P. Fuenzalida Werner, E. Anaya Plaza, M. A. Kostiainen, R. D. Costa

This paper develops a method to stabilize fluorescent proteins in lighting devices using FP-apoferritin cocrystals, reducing device temperatures and improving stability.

bioRxiv · Oct 17, 2023Bioengineering

Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii

C. Jonkergouw, N. K. Beyeh, E. Osmekhina, K. Leskinen, S. M. Taimoory, D. Fedorov, E. Anaya-Plaza, M. A. Kostiainen, J. F. Trant, R. H. A. Ras, P. Saavalainen, M. B. Linder

This paper identifies Pillar[5]arene, a synthetic macrocycle that targets virulence factors in multidrug-resistant bacteria, reducing biofilms and enhancing antibiotic efficacy.

bioRxiv · Mar 1, 2023 · PreprintBiochemistry

Reconfigurable pH-Responsive DNA Origami Lattices

S. Julin, V. Linko, M. A. Kostiainen

This paper demonstrates a pH-responsive DNA origami lattice that can be reversibly switched between states using pH changes, with applications in forming reconfigurable 2D gold nanoparticle lattices.

bioRxiv · Feb 3, 2023Bioengineering

DNA origami directed virus capsid polymorphism

I. Seitz, E.-P. Kumpula, E. Anaya-Plaza, J. J. Cornelissen, V. Linko, J. T. Huiskonen, M. A. Kostiainen

This paper demonstrates DNA origami-directed polymorphism of viral capsids, showing control over shape, size, and topology through programmable assembly platforms.

bioRxiv · Nov 7, 2022Bioengineering

Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release

H. Ijäs, B. Shen, A. Heuer-Jungemann, A. Keller, M. A. Kostiainen, T. Liedl, J. A. Ihalainen, V. Linko

This study characterizes and optimizes doxorubicin loading into DNA origami nanostructures, revealing rapid binding and variable release profiles influenced by nanostructure design and environmental factors.

bioRxiv · May 13, 2020Biochemistry