Author

M. A. LaPorta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Davis· 2 shared A. Gandhi· 2 shared A. P. Havas· 2 shared A. Rajesh· 2 shared G. Garcia· 2 shared P. D. Adams· 2 shared X. Lei· 2 shared A. B. Lagnado· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMolecular Biology

A. Davis

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Author profile →

2 papers

Recent·Most cited

Age-associated repression of HNF4α is a driver and potential therapeutic target in liver metabolic dysfunction

Jessica Proulx, K. A. Lande, X. Lei, A. P. Havas, M. Garcia Teneche, A. Rajesh, H. Tanaka, M. A. LaPorta, G. Evensen, S. Mamde, L. Wang, A. Gandhi, R. Arnold, A. Davis, A. Liou, , P. D. Adams

This study identifies age-associated repression of HNF4α as a driver of liver metabolic dysfunction and shows that restoring HNF4α can reverse some age-related liver defects.

bioRxiv · Nov 9, 2026 · PreprintMolecular Biology

Linked regulation of genome integrity and senescence-associated inflammation by p53

K. N. Miller, B. Li, H. R. Pierce-Hoffman, S. Patel, X. Lei, A. Rajesh, M. G. Teneche, A. P. Havas, A. Gandhi, C. Cano Macip, J. Lyu, S. G. Victorelli, S.-H. Woo, A. B. Lagnado, M. A. LaPorta, , P. D. Adams

This study identifies a mitochondria-regulated p53 circuit that links genomic instability and inflammation in senescent cells, showing p53 suppresses inflammation without affecting cell cycle arrest.

bioRxiv · Nov 20, 2023 · PreprintCell Biology