Author

M. A. McGuckin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

E. C. Hoedt· 2 shared J. Begun· 2 shared M. Morrison· 2 shared K. Shamsunnahar· 1 shared P. O Cuiv· 1 shared P. O. Cuiv· 1 shared R. Giri· 1 shared R. Giria· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

E. C. Hoedt

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2 papers

Recent·Most cited

Secreted microbial metabolites modulate gut immunity and inflammatory tone

R. Giri, E. C. Hoedt, K. Shamsunnahar, M. A. McGuckin, M. Morrison, R. J. Capon, J. Begun, P. O. Cuiv

The paper identifies gut bacteria that suppress NF-κB activity and inflammatory responses, suggesting microbiome modulation as a potential therapeutic strategy for IBD.

bioRxiv · Dec 16, 2019 · PreprintMicrobiology

Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses NF-kB activation in human gut epithelial cells

P. O Cuiv, R. Giria, E. C. Hoedt, M. A. McGuckin, J. Begun, M. Morrison

The paper isolates and characterizes E. faecalis AHG0090, showing it suppresses NF-κB activation in human gut cells and produces a heat- and protease-resistant peptidic bioactive.

bioRxiv · Mar 3, 2018Microbiology