Cell BiologybioRxiv
Leptin promotes expression of EMT-related transcription factors and invasion in a Src and FAK-dependent pathway in MCF10A mammary epithelial cells
M. Olea-Flores, M. Zuniga-Eulogio, A. Tacuba-Saavedra…·N. Navarro-Tito
This study shows leptin induces EMT and invasion in MCF10A cells via Src and FAK activation, increasing Twist and β-catenin expression and MMP secretion.
DOI 10.3390/cells8101133