T. PADILLA-BENAVIDES

Single nucleotide polymorphisms and Zn transport by nuclear ZIP11 shape cancer phenotypes in HeLa cells

The paper investigates how SNPs in ZIP11 and its Zn-binding site affect Zn transport and carcinogenic properties in HeLa cells.

Functional effect of indole-3 carbinol in the viability and invasive properties of cultured cancer cells.

This study examines the effects of indole-3-carbinol on cancer cell viability, migration, invasion, and mitochondrial integrity in hepatoma, breast, and cervical cancer cell lines, showing reduced carcinogenic properties and altered mitochondrial membrane potential.

The mitochondrial Cu+ transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro

This study identifies PiC2 as a copper transporter regulated by MTF1, essential for skeletal muscle myoblast proliferation and differentiation by delivering copper to COX.

CK2-dependent phosphorylation of the Brg1 chromatin remodeling enzyme occurs during mitosis

This study shows CK2 phosphorylates Brg1 during mitosis, affecting its localization and subunit interactions in multiple cell types.

Leptin promotes expression of EMT-related transcription factors and invasion in a Src and FAK-dependent pathway in MCF10A mammary epithelial cells

This study shows leptin induces EMT and invasion in MCF10A cells via Src and FAK activation, increasing Twist and β-catenin expression and MMP secretion.

MTF1, a classic metal sensing transcription factor, promotes myogenesis in response to copper.

This study identifies a role for MTF1 and copper in promoting myogenesis by enhancing MTF1 expression and its interaction with myogenic genes.

Leptin induces cell migration and invasion in a FAK-Src- dependent manner in breast cancer cells

This study shows leptin promotes breast cancer cell migration and invasion through FAK and Src kinases, and increases MMP-2 and MMP-9 secretion.

Ouabain enhances cell-cell adhesion mediated by β1-subunits of the Na+,K+-ATPase in CHO fibroblasts.

This study shows that ouabain increases cell-cell adhesion in CHO fibroblasts expressing the β1 subunit of Na+,K+-ATPase by enhancing its membrane expression and activating c-Src.

Manganese influx and expression of ZIP8 is essential in primary myoblasts and contributes to activation of SOD2

The paper investigates the role of ZIP8 and ZIP14 in manganese transport and SOD2 activity during skeletal muscle differentiation, showing ZIP8's essential function in myoblast growth and survival.