The First Inhibitor of Meso-Diaminopimelate Biosynthesis with Antibacterial Activity Against Multi-Drug Resistant Bacteria
T. P. Soares da Costa, J. A. Wyllie, C. K. Ghardi, M. D. Hulett, B. M. Abbott, M. Sutton, M. A. Perugini
This paper identifies the first inhibitor of meso-DAP biosynthesis with antibacterial activity against multi-drug resistant A. baumannii, showing efficacy against carbapenem-resistant strains and biofilm disruption.
bioRxiv · Feb 10, 2022 · PreprintMicrobiology