T. P. Soares da Costa

This paper investigates the mode of action of herbicidal lysine biosynthesis inhibitors, showing they inhibit a second enzyme and extend analyses to a globally significant weed species.

This paper identifies the first inhibitor of meso-DAP biosynthesis with antibacterial activity against multi-drug resistant A. baumannii, showing efficacy against carbapenem-resistant strains and biofilm disruption.

This study identifies plant DHDPS inhibitors as a novel herbicide target, showing they inhibit lysine biosynthesis and demonstrate herbicidal activity against Arabidopsis thaliana.

This study determines the crystal structures of TANV16L bound to Bax, Bim, and Puma BH3, revealing its mechanism of inhibiting apoptosis by adopting monomeric and dimeric forms while maintaining the canonical ligand binding groove.