A Single Dose of Self-Transcribing and Replicating RNA Based SARS-CoV-2 Vaccine Produces Protective Adaptive Immunity In Mice
R. M. de Alwis, E. S. Gan, S. Chen, Y. S. Leong, H. C. Tan, S. L. Zhang, C. Yau, D. Matsuda, E. Allen, P. Hartman, J. Park, M. Alayyoubi, H. Bhaskaran, A. Dukanovic, B. Bao, , E. E. Ooi
A single dose of the STARR-based SARS-CoV-2 vaccine LUNAR-COV19 induces protective adaptive immunity in mice, including strong antibody and CD8+ T cell responses, and full protection against viral challenge.
bioRxiv · Sep 3, 2020Immunology