Author

H. C. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

E. E. Ooi· 2 shared A. Dukanovic· 1 shared a. M. Bifani· 1 shared A. Manglik· 1 shared A. Pizzorno· 1 shared B. Bao· 1 shared B. Clemente· 1 shared B. Faust· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

E. E. Ooi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell strain-derived induced pluripotent stem cell as a genetically controlled approach to investigating aging mechanisms and viral pathogenesis

a. M. Bifani, H. C. Tan, M. M. Choy, E. E. Ooi

This study uses iPSC-derived cell strains to investigate how aging impacts dengue virus-host interactions and pathogenesis.

bioRxiv · May 11, 2021 · PreprintMicrobiology

A Single Dose of Self-Transcribing and Replicating RNA Based SARS-CoV-2 Vaccine Produces Protective Adaptive Immunity In Mice

R. M. de Alwis, E. S. Gan, S. Chen, Y. S. Leong, H. C. Tan, S. L. Zhang, C. Yau, D. Matsuda, E. Allen, P. Hartman, J. Park, M. Alayyoubi, H. Bhaskaran, A. Dukanovic, B. Bao, , E. E. Ooi

A single dose of the STARR-based SARS-CoV-2 vaccine LUNAR-COV19 induces protective adaptive immunity in mice, including strong antibody and CD8+ T cell responses, and full protection against viral challenge.

bioRxiv · Sep 3, 2020Immunology

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

B. Wang, D. Asarnow, W.-H. Lee, C.-W. Huang, B. Faust, P. M. L. Ng, E. Z. X. Ngoh, M. Bohn, D. Bulkley, A. Pizzorno, H. C. Tan, C. Y. Lee, R. A. Minhat, O. Terrier, M. K. Soh, , C.-I. Wang

This study identifies a potent SARS-CoV-2 neutralizing antibody, 5A6, that binds bivalently to two RBDs on the spike protein, showing resistance to key mutations.

bioRxiv · Jul 14, 2020 · PreprintMicrobiology