Cell BiologybioRxivPreprint
Multiple routes of adaptation to high levels of CIN and aneuploidy in budding yeast
M. N. Clarke, T. Marsoner, M. Alonso Y Adell…·C. S. Campbell
This study shows yeast cells adapt to high chromosomal instability and aneuploidy by first acquiring beneficial aneuploidies, then developing suppressor mutations, and finally reducing aneuploidy levels.
DOI 10.1101/2022.04.21.489003