Multiple routes of adaptation to high levels of CIN and aneuploidy in budding yeast
M. N. Clarke, T. Marsoner, M. Alonso Y Adell, M. C. Ravichandran, C. S. Campbell
This study shows yeast cells adapt to high chromosomal instability and aneuploidy by first acquiring beneficial aneuploidies, then developing suppressor mutations, and finally reducing aneuploidy levels.
bioRxiv · Apr 21, 2022 · PreprintCell Biology