Decoding of T cell immunodominance patterns by an integrated mechanistic approach
M. Alvaro-Benito, E. T. Abualrous, H. Lingel, S. Meltendorf, J. Holzapfel, P. de Diego Valera, J. Sticht, B. Kuropka, C. Clementi, F. Kuppler, M. C. Brunner-Weinzierl, C. Freund
The paper identifies immunodominant CD4+ T cell epitopes for SARS-CoV-2 antigens by integrating antigen processing systems with in silico tools, revealing distinct processing mechanisms for different antigens.
bioRxiv · Jan 10, 2024 · PreprintImmunology